Chelsea host Barclays Women’s Super League leaders Manchester City at Stamford Bridge early Saturday afternoon.
Both sides are still without a win in the WSL this season, with Manchester City holding a two-point lead at the top.
City boss Andrée Jeglertz is hopeful that Vivianne Miedema, Beth Mead, and Niamh Charles will be available after spells out.
Meanwhile, looking ahead to the game, Chelsea captain Erin Cuthbert told chelseafc.com: “I expect it to be a very high-quality game, but also to be quite edgy at the same time, because both teams want to win, but both teams don’t want to lose.
“So it’s a fine balance between whether you go and risk it all, or hold on to what you’ve got. I know the team will go for it right until the final whistle, and if we’re still in it, we’ll be going gung-ho, and if we are winning, we’ll fight to keep it that way.”
Manchester United and Crystal Palace kick off the weekend’s fixtures, both securing a victory in their last outing.
Saturday’s matches continue with Spurs hosting Everton and Brighton facing Liverpool in the late kick-off, with the Reds just a couple of points above the bottom two.
Sunday brings three derbies, starting with Aston Villa against Birmingham City, who sit next to bottom.
West Ham welcome Charlton Athletic, who are still to get off the mark after nine games.
Last in the schedule, but certainly not least, is Arsenal taking on third-placed London City Lionesses.
WSL2 features a massive Wear-Tyne derby, which is also a top-of-the-table clash.
Sunderland have home advantage, but Newcastle United are unbeaten and lead the league by three points.
Third-placed Ipswich are at mid-table Watford, while Nottingham Forest sit fourth and host an East Midlands derby with Leicester City.
Burnley look for a first win when home against Southampton, Wolves face a Durham side yet to pick up a point, and Sheffield United versus Bristol City is a Saturday evening kick-off.
Saturday 14 November
Barclays WSL
Manchester United v Crystal Palace (Leigh Sports Village, 12.45pm) – Live on Sky Sports
Chelsea v Manchester City (Stamford Bridge, 1.30pm) – Live on BBC
Tottenham Hotspur v Everton (Leyton Orient FC, 3pm) – Live on Sky Sports
Brighton & Hove Albion v Liverpool (AMEX Stadium, 5.15pm) – Live on Sky Sports / YouTube
Barclays WSL 2
Sheffield United v Bristol City (Bramall Lane, 6pm) – Live on WSL2 YouTube
Sunday 15 November
Barclays WSL
Aston Villa v Birmingham City (Villa Park, 2pm) – Live on Sky Sports
West Ham United v Charlton Athletic (Dagenham & Redbridge FC, 2pm) – Live on Sky Sports / YouTube
Arsenal v London City Lionesses (Emirates Stadium, 4.30pm) – Live on Sky Sports
Barclays WSL2 – All live on WSL2 YouTube
Burnley v Southampton (Turf Moor, 2pm)
Nottingham Forest v Leicester City (City Ground, 2pm)
Sunderland v Newcastle United (Stadium of Light, 2pm)
Watford v Ipswich Town (Vicarage Road Stadium, 2pm)
Wolverhampton Wanderers v Durham (AFC Telford Utd, 2pm)
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